Nattokinase is made from natto, a Japanese food that is fermented soy beans. This popular dish has been served in Japan for over one thousand years. One of the enzymes from this food product has some direct fibrinolytic activity. Although Nattokinase is under-researched, it appears to reduce the risk of a cardiovascular incident by reducing the formation of blood clots. If you are searching for a natural blood clot buster, discuss the benefits of Nattokinase with your health care provider.